PCOS ranks as one of the most common sources of infertility issues among women; 5% to 10% of women who are in their childbearing have PCOS. However, most of these women are unaware that they have the disease and even lesser have an idea of what it’s about it. Normally, women who are suffering from PCOS only learn about their conditions when attempting to get pregnant.
There are no known exact cause or causes of PCOS, however studies show that there is a strong relationship between PCOS and insulin resistance in the body. As hormonal imbalance occurs, the female produces more male hormones known as androgen and lesser number of female hormones. In normal females, this is what happens. During the monthly cycle, there are 20 follicles developed within the ovaries, an egg grows inside of every follicle and as the menstrual cycle progresses, one of these 20 follicles will remain to release its eggs during ovulation nad once that egg is developed, the level of LH increases, as that happens the egg breaks loose thus paving the way for ovulation.
However, among women with PCOS, there is not enough amount of female hormones produced as there is hormonal imbalance. Unlike normal women, the follicles do not create the eggs instead these follicles turn into cysts. When there is no egg, there is no ovulation and ovulation is the key to fertility.
Fortunately however, there are solutions to the infertility caused by PCOS. Like what was mentioned earlier, ovulation is the key to fertility; therefore the key is to make a woman ovulate and this can be done through medications and procedures. Normally, the first step is to lose weight first, as women with PCOS are obese or overweight, they are asked to exercise and stick to a diet to shed the extra pounds. This is because losing weight affects the level of insulin in he body and when the extra amount of insulin used, the hormonal imbalance may be corrected thus the ovulation may be normalized as well.
In other cases, doctors usually prescribe the drug Metformin. This is a type of medicine that improves the ability of the body to process insulin. Normally, this is given to women with no diabetes because it only affects the level of insulin in he body but does nothing to decrease the amount of blood sugar in the body, which is an important factor for diabetics.
While Metformin is generally the first drug recommended, Clomid comes in second. Unlike the first drug, Clomid directly affects the estrogen receptors in one’s brain thus hampering its sensitivity to the said hormone. It makes the brain think that the estrogen level is very low thus resulting to higher levels of FSH and LH in the body; this triggers the ovulation. According to reports, around 35% to 40% of Clomid users had successful pregnancies.
When over the counter drugs won’t work, a more complex procedure is offered; this is known as In – Vitro Fertilization where the eggs are harvested and then grown in a laboratory. Once fertilized they are brought back to the womb with higher chances of pregnancy.